EDD stands for Estimated Date of Delivery, while EDC stands for Estimated Date of Confinement. The bioZhena thinking, in one brief sentence, is: Aim to replace stochastic with deterministic, which is also the purpose of our eukairosicTM diagnostic tools.
The medical position on current status of obstetrics can be characterized by the following two papers.
1) Theory of obstetrics: an epidemiologic framework for justifying medically indicated early delivery [BMC Pregnancy Childbirth. 2007 Mar 28;7:4. Joseph KS, Perinatal Epidemiology Research Unit, Department of Obstetrics & Gynaecology, Dalhousie University, Halifax, Nova Scotia, Canada]
QUOTE: Modern obstetrics is faced with a serious paradox. Obstetric practice is becoming increasingly interventionist … Whereas … mortality declines exponentially with increasing gestational duration, temporal increases in medically indicated labour induction and cesarean delivery have resulted in rising rates of preterm birth and declining rates of postterm birth. … [This] provides a theoretical justification for medically indicated early delivery and reconciles the contemporary divide between obstetric theory and obstetric practice. END QUOTE.
And 2) A re-look at the duration of human pregnancy [Singapore Med J. 2006 Dec;47(12):1044-8. Bhat RA and Kushtagi P, Department of Obstetrics and Gynaecology, Kasturba Medical College, Manipal, India]
QUOTE: The duration of human pregnancy is arbitrarily taken as 280 days (40 weeks). Foetuses are considered to be at high risk once pregnancy goes beyond the expected date of confinement. … Conclusion: Mean gestational age at the onset of labour for women native to the area of study was 272 days (standard deviation 9 days). Pregnancies beyond a duration of 280 days showed significantly increased perinatal morbidity. It is suggested that there is a need for determining the length of gestation and to compile gestation-wise incidence of … neonatal morbidity indicators for different populations. END QUOTE.
Related articles are here.
I will rely on the birthing specialist, Janelle Durham, to verbalize for you the status quo in this aspect of the homo sapiens experience – below.
Per Encyclopedia of Childhood and Adolescence, article Gestation Period and Gestational Age ,
” a gestation period of thirty-eight weeks (266 days) is calculated for women who are pregnant by a procedure such as in vitro fertilization or artificial insemination that allows them to know their exact date of conception.”
The Ovulona device from bioZhena will provide to the woman user a very simple means to record the day of any intercourse. In every cycle, whether pregnancy is planned or not. This must become a part of the routine. The information will be electronically recorded along with the daily or almost-daily measurement data inherent in the use of the Ovulona. With that menstrual cycling history data, this intercourse-timing information will be available for optional use by the woman’s physician(s).
Therefore, the routine use of the Ovulona will provide for an equivalent of the above-referenced 38-week (266 days) calculation available to the women receiving IVF or artificial insemination.
This alone should be an improvement on the current way of EDD/EDC assessment.
In this context, an investigation should be undertaken into the question of whether any inference can be drawn from the woman’s menstrual cycle history prior to the conceptive intercourse. Any comments on this would be welcome, even about anecdotal or subjective or tentative observations that may be available. However non-scientific, however tentative, however uncertain an individual answer or input from you may be…
Questions.
E.g., do women with more or less regular cycles tend to exhibit a regular gestation period, and vice versa?
And, certainly, what evidence is available in medical literature (or maybe in unpublished records?) about the outcomes of the IVF and/or artificial insemination pregnancies, i.e., about their documented gestation periods? Does the 38 weeks projection work? Always? If not always, can anything be correlated with any deviation?
Do women with distinctly irregular menstrual cycles tend to have non-regular gestation periods?
The complicating effect of first versus subsequent pregnancy has already been noted, of course… That evidence exists for gestational length variability with ethnicity (or race) has also been noted [International Journal of Epidemiology 2004, Volume 33, Number 1, pp. 107-113 ].
Conceivably, there is no such preliminary info available, and we shall have to try and gather even these preliminary data in a systematic manner, but – no question asked, nothing learned… Public or private input would be appreciated. [Private at vaclavkirsner at yahoo.com, please, if you prefer to communicate privately.]
There actually would seem to be a fairly good basis for this attempt at an online inquiry (or survey), in preparation for an introduction of a tool with which to study the subject further. -
According to the due dates paper by Janelle Durham, written for Certification with Birth Education in January, 2002 ,
QUOTE: “some women are aware of when they ovulate, either based on formal methods and record-keeping such as daily temperature checks, or on physical symptoms such as mild pain upon ovulation, or observation of changes in vaginal mucus.
Many women know the dates when conception was possible, because they know the dates when they had intercourse during their most recent menstrual cycle. Due dates can be calculated based on these dates, but many physicians prefer to calculate it from date of last menstrual period. They may only calculate from conception date if conception was medically managed and supervised through techniques such as artificial insemination.
Based on date of last normal menstrual period. Due dates are typically calculated based upon the date the last menstrual period began, according to the mother’s report. Naegele’s rule assumes that ovulation occurred 14 days after LMP, which is only the case for women with 28 day cycles.
Some caregivers will ask their patients for a history of menstrual cycles so that they can adjust this number, as appropriate, for cycles of different lengths or irregular cycles. It’s also important to consider: recent use of oral contraceptives, and their possible effect on ovulation date; inaccurate memory about when the last period occurred, the possibility of interpreting post-conception ‘spotting’ as a light period, and unrecognized pregnancy losses.
These issues all complicate due date prediction, and it’s estimated that nearly 25% of infants who would be classified as preterm birth on the basis of the last normal menstrual period are not preterm. (Cited in Health Canada)” END QUOTE.
At this point, let me translate the one brief sentence I wrote at the top into a less specialist language. Ms. Durham shows a statistical distribution of gestation periods applicable to any woman, and that is the approach I labeled stochastic, because of its statistical nature.
I admit, the word is harking back to the days of my postgrad phys chem endeavors, which were mostly endeavours at the time.
We could also say, probabilistic – two syllables longer, though!
http://transitiontoparenthood.com/ttp/birthed/duedatespaper.htm
With our eurokairosicTM diagnostic tools, we generally aim to determine the right time, and in the case at hand we would like to provide for a much less fuzzy assessment of the EDD and EDC. After all, precedent exists in the A.R.T. arena, and prerequisites, too, to some extent at least. In a nutshell, let’s try to replace the LMP/Naegele-based approach with a hard data-based technique, applied to each and by each Mom individually.
Again, your comments and answers to the questions above would be very useful. Public or private input would be appreciated. [Private at vaclavkirsner at yahoo.com, please, if you prefer private.]
Tags: aid, ART, assisted reproductive technologies, at-home, awareness, baby, Billings, bio-electronic, bioelectrochemistry, biology, bioPecus, biophysical, biosensor, bioZhena, birth, birthday, birthing, business, cervical, cervix, cervix uteri, colposcope, commercialization, company, conception, conceptive, consumer, contraception, control, COPE score, Corporation, Creighton, development, diagnosis, dystocia, EDC, EDD, electrochemistry, electronic, electronics, embryo, emerging, end-organ effect, endocrinology, entrepreneurship, epithelium, estimated day of confinement, estimated day of delivery, FAM, family, fecundability, fecundity, female, fertility, fetal, fetus, follicular phase, folliculogenesis, fornix, founder, gender, gynecology, health, Hilgers, home, hormone, hot flash, hot flush, HRT, infertility, innocuous, intercourse, intravaginal, investment, KIrsner, last menstrual period, life, LMP, luteal phase, medical, medicine, menopause, Mortola, mucus, natural, NFP, non-chemical, obgyn, obstetrics, offering, opportunity, ovarian, ovary, ovulation, Ovulona, parturition, parturition alarm, peri-menopause, period, phase, physiology, placement, planning, PMDD, PMS, population, PPM, pregnancy, premenstrual, preselection, prevention, private, psychiatric instrument, psychoneuroendocrinology, psychosomatic, R&D, reduced, replacement, reproductive, research, science, scientist-entrepreneur, selection, self-diagnosis, self-help, sensor, sex, short luteal phase, sperm, start-up, startup, status, stress, sub-fertility, subfertility, subscription, syndrome, technology, therapy, timing, tissue, tool, Vaclav, Vaclav Kirsner, vaclavkirsner, vagina, vaginal, vaginal insert, venture, women's, zoology

August 17, 2009 at 7:44 am |
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