Ovulography and the Ovulograph

The concept of ovulographyTM is as follows:

a) the menstrual cyclic profile captured by the OvulonaTM is diagnostically useful for women’s healthcare providers (meaning physicians, nurses and also insurance payment/reimbursement decision-makers), and  

b) correlating the menstrual cyclic profile data with symptoms or other observables in the course of managing a female patient is of fundamental importance to the doctor (re: precision medicine, evidence-based medicine).

The diagnostic usefulness – brought up above in the item a) link, in which the references are clickable [unlike in the image] – is illustrated in this composite image:

How Ovulona will help physicians AND Ovulograph for menstrual cycle diagnosis - vertical

As indicated above the image, the hyperlinks to the referenced further particulars are accessible above via the link in part a) of the opening statement of the concept of bioZhena’s ovulography (diagnostically useful).

The links to the lower part of the image, “Ovulograph for menstrual cycle diagnosis”, are accessible via https://biozhena.files.wordpress.com/2019/08/ovulograph-single-slide-menstrual-cycle-diagnosis-r.-legro-ref..pps .

Next follows a shorthand pictorial representation of the biological underpinnings of the modus operandi of the ovulographic (cervix tracking) technique and a summary of the baseline and non-baseline (“real-life”) menstrual cycle profile signatures generated in pilot studies testing prototypes of the Ovulona.

HPG slide shot e1 w.modif. text(&or) & innervation on right AND Figs. 2&5 vertical with text

Let the prospective diagnostic usefulness of ovulographyTM be highlighted by sketching examples of facilitating differential diagnosis (here PMS/PMDD vs. clinical depression), the effects of stress on fertility, and the unprecedented ability to anticipate the failure to ovulate in the current menstrual cycle (of great importance to subfertile and infertile couples):


View these four slides as a hint at how the bioZhena ovulographicTM technology will help women’s physicians. Let’s focus on how it will “…shed light on premenstrual dysphoric disorder (PMDD)… [They] first need to find out which monthly rhythm the brain of a healthy woman follows to reveal the differences in people affected by PMDD” (cited from “Menstrual Cycle Helps Female Brain Grow: Estrogen Levels Boost Volume Of Hippocampus During Ovulation” at http://www.medicaldaily.com/menstrual-cycle-helps-female-brain-grow-estrogen-levels-boost-volume-401295).

It is the notion that “they first need to find out which monthly rhythm the brain of a healthy woman follows” where ovulography comes in and provides for a measurable comparison between the healthy and the ill, and between before and after treatment. A routinely and affordably measurable comparison directly reporting the “monthly rhythm”, ovulography is far less demanding – while more accurate – than the currently available methods. Thereby significantly improving access to care for the many PMS/PMDD sufferers. Improving the much needed – and currently sorely lacking – quality of care is to be expected.

As the Medical Daily article indicated, “Barth and her team of researchers observed 30 women and measured the levels of estrogen in their blood across two full menstrual cycles. The women also underwent MRI scans, which the researchers used to measure the volume of the different regions within each woman’s brain.”

Our ovulographicTM technology brings significant advantages into the PMS/PMDD field. It provides the folliculogenesis and the symptometric data that are needed for the MRI brain scan research, and separately it provides a practical medical routine means for administering therapy based on individual patients’ monitoring in the comfort of their home.

Ovulographic Correlation of Folliculogenesis and Symptometric Data

For more about PMS and PMDD, go to https://biozhena.wordpress.com/2007/12/17/premenstrual-syndrome-pms-and-pmdd/ .

For more about the Ovulona sensor, go to https://biozhena.wordpress.com/the-ovulona/.





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